journal reprint

Distribution and Changes in m- and k-Opiate Receptors During the Midlife Neurodevelopmental Period of Coho Salmon, Oncorhynchus kisutch

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Description

In preparation for leaving natal streams and beginning ocean migration, coho salmon undergo a transformation that includes physiological and behavior changes called parr-smolt transformation. This study demonstrates the extensive and selective distribution of m- and k-opioid receptors and their change in ligand binding during parr-smolt transformation. It is the first study of opioid receptor subtypes in salmonid brains, and the first investigation of opioid receptors in the brain of a teleost during development. Journal of Comparative Neurology 364:448-464, 1996.